PUBLICATIONS

We handle and analyze all types of data: from human genetic information to industrial process readings. Our clients include large and small academic laboratories, medical device manufacturers, biotechnology companies and the public sector.

Crowdsourcing temporal transcriptomic coronavirus host infection data: Resources, guide, and novel insights.

2023

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/38107402/

Authors:

Flynn J, Ahmadi MM, McFarland CT, Kubal MD, Taylor MA, Cheng Z, Torchia EC, Edwards MG.

Journal:

Biol Methods Protoc. 2023 Nov 14;8(1).

Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model.

2023

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/36961489/

Authors:

Brown RD, Hunter KS, Li M, Frid MG, Harral J, Krafsur GM, Holt TN, Williams J, Zhang H, Riddle SR, Edwards MG, Kumar S, Hu CJ, Graham BB, Walker LA, Garry FB, Buttrick PM, Lahm T, Kheyfets VO, Hansen KC, Stenmark KR.

Journal:

Am J Physiol Heart Circ Physiol. 2023 Jun 1;324(6):H804-H820.

Delay modulates the immune response to nerve repair.

2023

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/36849720/

Authors:

Golshadi M, Claffey EF, Grenier JK, Miller A, Willand M, Edwards MG, Moore TP, Sledziona M, Gordon T, Borschel GH, Cheetham J.

Journal:

NPJ Regen Med. 2023 Feb 27;8(1):12.

Transcriptome and metabolome changes induced by bitter melon (Momordica charantia)- intake in a high-fat diet induced obesity model.

2021

Publication Year:

// URL:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039170/

Authors:

Reed D, Kumar D, Kumar S, Raina K, Punia R, Kant R, Saba L, Cruickshank-Quinn C, Tabakoff B, Reisdorph N, Edwards MG, Wempe M, Agarwal C, Agarwal R.

Journal:

J Tradit Complement Med. 2021 Aug 19;12(3):287-301.

The Suppression of Very Long Chain Fatty Acids Is Associated with Skin Carcinogenesis

2020

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/32240721/

Authors:

Cheema SK, Isesele PO, Marchando S, Edwards MG, Torchia EC.

Journal:

J Invest Dermatol. 2020 Nov;140(11):2291-2294.

Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines in SHIVnef-Infected Macaques.

2018

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/29256819/

Authors:

Almodovar S, Swanson J, Giavedoni LD, Kanthaswamy S, Long CS, Voelkel NF, Edwards MG, Folkvord JM, Connick E, Westmoreland SV, Luciw PA, Flores SC.

Journal:

Viral Immunol. 2018 Apr;31(3):206-222.

The basophil proteome in chronic spontaneous urticaria distinguishes responders to omalizumab from non-responders.

2018

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/29671921/

Authors:

Stitt JM, Dzieciatkowska M, Edwards MG, Hansen K, Hedlund G, Dreskin SC.

Journal:

Clin Exp Allergy. 2018 Apr 19.

Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia.

2018

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/29997230/

Authors:

Merrick DT, Edwards MG, Franklin WA, Sugita M, Keith RL, Miller YE, Friedman MB, Dwyer-Nield LD, Tennis MA, O'Keefe MC, Donald EJ, Malloy JM, van Bokhoven A, Wilson S, Koch PJ, O'Shea C, Coldren C, Orlicky DJ, Lu X, Baron AE, Hickey G, Kennedy TC, Powell R, Heasley L, Bunn PA, Geraci M, Nemenoff RA.

Journal:

Cancer Res. 2018 Sep 1;78(17):4971-4983.

Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy.

2017

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/29040318/

Authors:

Burchill MA, Roby JA, Crochet N, Wind-Rotolo M, Stone AE, Edwards MG, Dran RJ, Kriss MS, Gale M Jr, Rosen HR.

Journal:

PLoS One. 2017 Oct 17;12(10):e0186213.

Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome.

2017

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/28196122/

Authors:

Hoffman O, Burns N, Vadász I, Eltzschig HK, Edwards MG, Vohwinkel CU

Journal:

PloS one. 2017; 12(2):e0172116.

Free Fatty Acids Differentially Downregulate Chemokines in Liver Sinusoidal Endothelial Cells: Insights into Non-Alcoholic Fatty Liver Disease.

2016

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/27454769/

Authors:

McMahan RH, Porsche CE, Edwards MG, Rosen HR

Journal:

PloS one. 2016; 11(7):e0159217.

Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation.

2016

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/27907090/

Authors:

Bin L, Deng L, Yang H, Zhu L, Wang X, Edwards MG, Richers B, Leung DY

Journal:

PloS one. 2016; 11(12):e0167392.

Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors.

2015

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/26078295/

Authors:

Hensel J, Duex JE, Owens C, Dancik GM, Edwards MG, Frierson HF, Theodorescu D.

Journal:

Molecular cancer research : MCR. 2015; 13(9):1306-15.

Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication.

2015

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/25447848/

Authors:

Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M Jr, Shah VH, Rosen HR.

Journal:

Gastroenterology. 2015; 148(2):392-402.e13.

RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer.

2015

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/25516960/

Authors:

Griner EM, Dancik GM, Costello JC, Owens C, Guin S, Edwards MG, Brautigan DL, Theodorescu D.

Journal:

Molecular cancer research : MCR. 2015; 13(3):483-92.

Novel Role for γ-Catenin in the Regulation of Cancer Cell Migration via the Induction of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1).

2015

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/25925948/

Authors:

Sechler M, Borowicz S, Van Scoyk M, Avasarala S, Zerayesus S, Edwards MG, Kumar Karuppusamy Rathinam M, Zhao X, Wu PY, Tang K, Bikkavilli RK, Winn RA.

Journal:

The Journal of biological chemistry. 2015; 290(25):15610-20.

Transmitted/founder hepatitis C viruses induce cell-type- and genotype-specific differences in innate signaling within the liver.

2015

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/25714713/

Authors:

Mitchell AM, Stone AE, Cheng L, Ballinger K, Edwards MG, Stoddard M, Li H, Golden-Mason L, Shaw GM, Khetani S, Rosen HR.

Journal:

mBio. 2015; 6(2):e02510.

Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer.

2015

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/25728679/

Authors:

Bikkavilli RK, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, Edwards MG, Rathinam MK, Zhou T, Tauler J, Borowicz S, Lussier YA, Parr BA, Cool CD, Winn RA.

Journal:

Oncogene. 2015; 34(42):5317-28.

FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.

2014

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/24771645/

Authors:

Wynes MW, Hinz TK, Gao D, Martini M, Marek LA, Ware KE, Edwards MG, Böhm D, Perner S, Helfrich BA, Dziadziuszko R, Jassem J, Wojtylak S, Sejda A, Gozgit JM, Bunn PA Jr, Camidge DR, Tan AC, Hirsch FR, Heasley LE.

Journal:

Clinical cancer research : an official journal of the American Association for Cancer Research. 2014; 20(12):3299-309.

Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions.

2014

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/24346345/

Authors:

Nakachi I, Rice JL, Coldren CD, Edwards MG, Stearman RS, Glidewell SC, Varella-Garcia M, Franklin WA, Keith RL, Lewis MT, Gao B, Merrick DT, Miller YE, Geraci MW.

Journal:

Cancer prevention research (Philadelphia, Pa.). 2014; 7(2):255-65.

Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer.

2014

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/25225064/

Authors:

Nickerson ML, Dancik GM, Im KM, Edwards MG, Turan S, Brown J, Ruiz-Rodriguez C, Owens C, Costello JC, Guo G, Tsang SX, Li Y, Zhou Q, Cai Z, Moore LE, Lucia MS, Dean M, Theodorescu D.

Journal:

Clinical cancer research : an official journal of the American Association for Cancer Research. 2014; 20(18):4935-48.

Identification of novel gene signatures in patients with atopic dermatitis complicated by eczema herpeticum.

2014

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/25159465/

Authors:

Bin L, Edwards MG, Heiser R, Streib JE, Richers B, Hall CF, Leung DY.

Journal:

The Journal of allergy and clinical immunology. 2014; 134(4):848-55.

Protective role of IL-6 in vascular remodeling in Schistosoma pulmonary hypertension.

2013

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/23815102/

Authors:

Graham BB, Chabon J, Kumar R, Kolosionek E, Gebreab L, Debella E, Edwards M, Diener K, Shade T, Bifeng G, Bandeira A, Butrous G, Jones K, Geraci M, Tuder RM.

Journal:

American journal of respiratory cell and molecular biology. 2013; 49(6):951-9.

Role of IL-18 in second-hand smoke-induced emphysema.

2013

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/23392573/

Authors:

Kratzer A, Salys J, Nold-Petry C, Cool C, Zamora M, Bowler R, Koczulla AR, Janciauskiene S, Edwards MG, Dinarello CA, Taraseviciene-Stewart L.

Journal:

American journal of respiratory cell and molecular biology. 2013; 48(6):725-32.

hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression.

2013

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/23862015/

Authors:

Avasarala S, Van Scoyk M, Wang J, Sechler M, Vandervest K, Brzezinski C, Weekes C, Edwards MG, Arcaroli J, Davis RE, Bikkavilli RK, Winn RA.

Journal:

Biology open. 2013; 2(7):675-85.

Peripheral blood mononuclear cell gene expression in chronic obstructive pulmonary disease.

2013

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/23590301/

Authors:

Bahr TM, Hughes GJ, Armstrong M, Reisdorph R, Coldren CD, Edwards MG, Schnell C, Kedl R, LaFlamme DJ, Reisdorph N, Kechris KJ, Bowler RP.

Journal:

American journal of respiratory cell and molecular biology. 2013; 49(2):316-23.

Promoter G-quadruplex sequences are targets for base oxidation and strand cleavage during hypoxia-induced transcription.

2012

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/22583700/

Authors:

Clark DW, Phang T, Edwards MG, Geraci MW, Gillespie MN.

Journal:

Free radical biology & medicine. 2012; 53(1):51-9.

Need for rigor in design, reporting, and interpretation of transcriptomic biomarker studies.

2012

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/23162111/

Authors:

Walter ND, Bemis L, Edwards M, Ovrutsky AR, Chan ED.

Journal:

Journal of clinical microbiology. 2012; 50(12):4190-1; discussion 4192-3.

Mitogen-activated protein kinase phosphatase-1 modulates regional effects of injurious mechanical ventilation in rodent lungs.

2012

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/22582160/

Authors:

Park MS, He Q, Edwards MG, Sergew A, Riches DW, Albert RK, Douglas IS.

Journal:

American journal of respiratory and critical care medicine. 2012; 186(1):72-81.

Identification of growth arrest and DNA-damage-inducible gene beta (GADD45beta) as a novel tumor suppressor in pituitary gonadotrope tumors.

2011

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/21810943/

Authors:

Michaelis KA, Knox AJ, Xu M, Kiseljak-Vassiliades K, Edwards MG, Geraci M, Kleinschmidt-DeMasters BK, Lillehei KO, Wierman ME.

Journal:

Endocrinology. 2011; 152(10):3603-13.

Increased cell surface Fas expression is necessary and sufficient to sensitize lung fibroblasts to Fas ligation-induced apoptosis: implications for fibroblast accumulation in idiopathic pulmonary fibrosis.

2011

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/21632719/

Authors:

Wynes MW, Edelman BL, Kostyk AG, Edwards MG, Coldren C, Groshong SD, Cosgrove GP, Redente EF, Bamberg A, Brown KK, Reisdorph N, Keith RC, Frankel SK, Riches DW.

Journal:

Journal of immunology. 2011; 187(1):527-37.

Elevated DISC1 transcript levels in PBMCs during acute psychosis in patients with schizophrenia.

2011

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/22319686/

Authors:

Olincy A, House R, Gao B, Recksiek P, Phang TL, Sullivan B, Hollis JP, Hopkins J, Shade T, Edwards MG, Vianzon R, Griffiths C, Ceilley J, Helfrich RW, Ritvo J, Weis E, Weiss D, Gault J.

Journal:

Translational biomedicine. 2011; 2(1).

Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease.

2010

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/20973980/

Authors:

Moré JM, Voelker DR, Silveira LJ, Edwards MG, Chan ED, Bowler RP.

Journal:

BMC pulmonary medicine. 2010; 10:53.

Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response.

2008

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/18031569/

Authors:

Anderson RM, Barger JL, Edwards MG, Braun KH, O'Connor CE, Prolla TA, Weindruch R.

Journal:

Aging cell. 2008; 7(1):101-11.

Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program.

2007

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/17381838/

Authors:

Edwards MG, Anderson RM, Yuan M, Kendziorski CM, Weindruch R, Prolla TA.

Journal:

BMC genomics. 2007; 8:80.

Impairment of the transcriptional responses to oxidative stress in the heart of aged C57BL/6 mice.

2004

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/15246999/

Authors:

Edwards MG, Sarkar D, Klopp R, Morrow JD, Weindruch R, Prolla TA.

Journal:

Annals of the New York Academy of Sciences. 2004; 1019:85-95.

Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart.

2003

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/12595580/

Authors:

Edwards MG, Sarkar D, Klopp R, Morrow JD, Weindruch R, Prolla TA.

Journal:

Physiological genomics. 2003; 13(2):119-27.

Attenuated transcriptional responses to oxidative stress in the aged rat brain.

2002

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/12391591/

Authors:

Tong L, Toliver-Kinsky T, Edwards M, Rassin DK, Werrbach-Perez K, Perez-Polo JR.

Journal:

Journal of neuroscience research. 2002; 70(3):318-26.

Use of an antineoepitope antibody for identification of type-II collagen degradation in equine articular cartilage.

2001

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/11453476/

Authors:

Billinghurst RC, Buxton EM, Edwards MG, McGraw MS, McIlwraith CW.

Journal:

American journal of veterinary research. 2001; 62(7):1031-9.

APE/Ref-1 responses to oxidative stress in aged rats.

1998

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/9843154/

Authors:

Edwards M, Rassin DK, Izumi T, Mitra S, Perez-Polo JR.

Journal:

Journal of neuroscience research. 1998; 54(5):635-8.

APE/Ref-1 responses to ischemia in rat brain.

1998

Publication Year:

// URL:

https://pubmed.ncbi.nlm.nih.gov/9926839/

Authors:

Edwards M, Kent TA, Rea HC, Wei J, Quast M, Izumi T, Mitra S, Perez-Polo JR.

Journal:

Neuroreport. 1998; 9(18):4015-8.